§ 173.170 Aminoglycoside 3′-phosphotransferase II.
The food additive aminoglycoside 3′-phosphotransferase II may be safely used in the development of genetically modified cotton, oilseed rape, and tomatoes in accordance with the following prescribed conditions:
(a) The food additive is the enzyme aminoglycoside 3′-phosphotransferase II (CAS Reg. No. 58943–39–8) which catalyzes the phosphorylation of certain aminoglycoside antibiotics, including kanamycin, neomycin, and gentamicin.
(b) Aminoglycoside 3′-phosphotransferase II is encoded by the kan rgene originally isolated from transposon Tn5of the bacterium Escherichia coli.
?。╟) The level of the additive does not exceed the amount reasonably required for selection of plant cells carrying the kan rgene along with the genetic material of interest.
[59 FR 26711, May 23, 1994]
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